Lavandula stoechas (L) a Very Potent Antioxidant Attenuates Dementia in Scopolamine Induced Memory Deficit Mice

Effects of Different Coumarin- 3-Carboxamide Agents on Scopolamine Induced Learning and Memory Deficit in Mice

Introduction: It has been shown that three new synthetic coumarins-3-carboxamides including 3-fluorobenzilchloride, 4-fluorobenzilchloride and 2-hidroxy-3 metoxybenzaldehyde, have acetylcholinesterase inhibitory activity. This study was performed to estimate ameliorating effect of these new coumarin-3-carboxamides on memory impairments induced by scopolamine (1 mg/kg, induced prolongation) in m...

Evaluation of the effect of Cyperus rotundus L. in scopolamine-induced learning deficit in mice

BACKGROUND Cyperus rotundus L. was used in traditional Iranian medicine to treat memory and cognition disorders. The present study was aimed at investigating the effect of the extract and essential oil of C. rotundus on memory dysfunction. MATERIALS AND METHODS Cognition was evaluated using the object recognition task that was composed of a square wooden open field box with different shape ob...

evaluation of the effect of cyperus rotundus l. in scopolamine-induced learning deficit in mice

The chemical constituents and biological activity of essential oil of Lavandula stoechas ssp. stoechas.

The composition of essential oil of the leaves of Lavandula stoechas ssp. stoechas, was analyzed by means of capillary GC-MS. The main components of L. stoechas ssp. stoechas oil were pulegone (40.4%), menthol (18.1%), menthone (12.6%). The essential oil of the plant was evaluated for antibacterial and a panel cytotoxic activities.

Curcumin-Loaded BSA Nanoparticles Protect More Efficiently Than Natural Curcumin Against Scopolamine-Induced Memory Retrieval Deficit

Introduction: There is evidence indicating that the rate of AD is lower in curry consuming populations. Then, there is an effort to elucidate if curcumin -as the main ingredient of turmeric- might affect the process of AD. However, in clinical trials of AD, a six-month curcumin treatment failed to show any progress, which might be attributable to its low bioavailability. In this line, a recent ...